Platelet Rich Fibrin in Periodontal Regeneration
نویسندگان
چکیده
Periodontitis is a chronic bacterial infection resulting in destruction of the supporting structures of the teeth. Regeneration of the lost tissues has faced difficulties primarily due to the lack of support during the intricate healing processes. A surgical additive which can 'jump start' the healing process to a more predictable regenerative process is always on the wish list of any periodontist. Platelet-rich fibrin (PRF) is a second generation platelet concentrate that has been considered to be an important, easy to obtain, predictable surgical additive for periodontal regeneration. This autologous scaffold provides the much needed bio-chemical mediators which has the potential for enhancing reconstruction of the periodontium. This review article tries to understand as to why PRF would be an important link to reach predictable periodontal regeneration.
منابع مشابه
Design and Fabrication of a Novel Transplant Combined with Human Bone Marrow Mesenchymal Stem Cells and Platelet-rich Fibrin: New Horizons for Periodontal Tissue Regeneration after Dental Trauma
Avulsed teeth that are replanted dried are more prone to loss. Recent tissue engineering studies focus onfabrication of various cell delivery systems to improve the overall prognosis of such teeth. To evaluate this newcell transplant method, we initially aimed at designing of PRF scaffold and determining BMMSCs viabilityand function on the fabricated scaffold. To test this concept in-vitro, hum...
متن کاملDesign and Fabrication of a Novel Transplant Combined with Human Bone Marrow Mesenchymal Stem Cells and Platelet-rich Fibrin: New Horizons for Periodontal Tissue Regeneration after Dental Trauma
Avulsed teeth that are replanted dried are more prone to loss. Recent tissue engineering studies focus onfabrication of various cell delivery systems to improve the overall prognosis of such teeth. To evaluate this newcell transplant method, we initially aimed at designing of PRF scaffold and determining BMMSCs viabilityand function on the fabricated scaffold. To test this concept in-vitro, hum...
متن کاملRegeneration Efficacy of Platelet-rich Fibrin in Patients Undergoing Periodontal Surgery: A Systematic Review and Meta-analysis
Periodontal surgery seeks for tissue regeneration. There is a new grafting material called platelet-rich fibrin (PRF), with multiple properties and one of them is regeneration. This study aimed to assess the regeneration efficacy of Platelet-rich fibrin in periodontal surgery. Were performed several computerized literature searches for randomized controlled trials (RCTs). That evaluated regener...
متن کاملSoft tissue regeneration using leukocyte-platelet rich fibrin after exeresis of hyperplastic gingival lesions: two case reports
INTRODUCTION Leukocyte-platelet rich fibrin belongs to a second generation of platelet concentrates that does not need biochemical blood manipulation. It is used for tissue healing and regeneration in periodontal and oral-maxillofacial surgery. We report two cases of hyperplastic gingival lesions treated by exeresis and application of leukocyte-platelet rich fibrin membranes in order to improve...
متن کاملPlatelet rich fibrin and nanocrystalline hydroxyapatite: hope for regeneration in aggressive periodontitis: A novel clinical approach
Periodontists have been experimenting various modalities for regeneration in Aggressive periodontitis with varying degrees of success. Periodontal surgery along with platelet rich fibrin (PRF) has yielded promising results. The purpose of this clinical trial was to evaluate the surgical outcome of an autologous growth factor obtained by sequestering and concentrating platelets by gradient densi...
متن کاملTreatment of a Intraosseous Defect with Platelet-rich fibrin (PRF) – A case report
Now a days Platelet-Rich Fibrin (PRF) is gaining more attention for obtaining periodontal regeneration. Platelet-rich fibrin (PRF) is considered a second-generation platelet concentrate that is widely used in osseous regeneration. The purpose of this case report is to present clinical and radiographic results of an intrabony periodontal defect treated with PRF. After surgical treatment with aut...
متن کامل